- “One last thing: as you raise your synchronization by executing events the way Ezio lived them, you might discover some... repressed memories.”
- ——Rebecca Crane to Desmond Miles.[来源]
Similarly to how Desmond Miles was only able to access the late memories of Altaïr Ibn-La'Ahad after reaching a high synchronization level with him, Rebecca Crane explains that these previously repressed memories would be unlocked in different points in Rome after gaining certain amounts of synchronization with Ezio Auditore.
In Florence, after being encouraged by his brother to try speaking with a pretty lady he saw passing on the street, Ezio instead stuttered and made himself look like a fool. Cristina left, though she smiled at his attempts, which Federico assured Ezio was a promising sign. Wishing for a second chance, Ezio decided to follow Cristina home to see where she lived. However, as Cristina passed through an alleyway, she met Vieri de' Pazzi standing at her door, who told her, "I'm tired of waiting for you to open your legs to me on your own." As he attempted to sexually assault her, Ezio stepped in and told Vieri that he seemed to be "disturbing this young lady's day." At this, Vieri started a fight with Ezio, but was sorely beaten. Thanking Ezio, Cristina told him her name and admitted that it looked like he had gotten his second chance.
Soon after the execution of Federico, Petruccio and Giovanni Auditore, Ezio sought to bury and give the final rites to his family. Ezio and Cristina arrived at the Palazzo della Signoria to retrieve their bodies, but after interrogating a guard, Ezio discovered that the bodies of his kin had already been taken to be dumped into the river. Ezio and Cristina hurried to the docks, where Ezio expalned he planed to kill the guards to get rescue his father's and brother's bodies. It was because of Cristina's plea's that he retrieved his kin one at a time to avoid being detected by the six guards on duty. After burning and setting the bodies adrift in the Arno, Ezio wished for Cristina to leave the city with him for Monteriggioni, but Cristina declined saying that she couldn't leave her family. Ezio responded by giving her a crest-shaped pendant, saying, "Now we'll always be together."
Ezio returned to Florence two years after his departure, in 1478, and met with Cristina, only to be told that she had thought he would never return, and that she was already engaged. Upon discovering that Cristina's fiance, Manfredo Soderini, was being attacked by men whom he owed a gambling debt to, Ezio came to his aid.
After rescuing him, Ezio dangled the man over a bridge and demanded to know if he truly loved Cristina. Manfredo sincerely replied that he did and if he died now he would die loving her, thus Ezio made him promise to be a faithful husband to Cristina, and to stop gambling otherwise he would hunt him down and kill him. Ezio then returned to Cristina, taking one last, long kiss from Cristinia. Then he tells her that he had made sure Manfredo would be a good husband to her. He then left abruptly, much to Cristina's confusion.
Upon learning from Leonardo da Vinci that Cristina was attending the Carnevale in Venice, with her husband Manfredo. Ezio wrote a fake note to Cristina to meet him in an alleyway, pretending to be her husband. Upon locating Cristina with Eagle Vision, Ezio planted the letter on her and waited at the meeting point. Unaware of Ezio's identity because of his mask, Cristina kissed Ezio, wondering why her husband had suddenly become so romantic. However, when she discovered who he was, she angrily pushed him away, stating incredulously that she hadn't seen him in eight years. As Ezio attempted to explain himself, Cristina interrupted him by saying that she had loved him, and not her fiance all those years ago, yet he had abandoned her to be married. She coldly said that his chance had passed, and told him to never look for her again.
In Florence in 1498, during the height of the Bonfire of the Vanities, Ezio found a dying Manfredo on the ground, who told him that Girolamo Savonarola's men had attacked their home, and that Cristina had fled with guards pursuing her. Ezio hunted down the guards and killed them, however Cristina had already been mortally wounded. Ezio attempted to carry Cristina to a doctor, only to have her die in his arms; however, not before Cristina showed him the pendant he had given her, which she had kept for the past twenty-two years out of a desire that they "could have had a second chance." As she closed her eyes, Ezio gave Cristina her last rites by quietly saying, "Requiescat in pace, my love."
- 在刺客信条：文艺复兴中，埃齐奥是从 马基雅维利嘴中得知克里斯蒂娜的死讯的
- 在第三个回忆中，埃齐奥穿着金属盔甲，美第奇披风以及装备着袖枪。 尽管当时他尚未拥有其中的任何一件东西
- 在克里斯蒂娜的回忆中埃齐奥都是手持阿泰尔之剑（从“最好的人”开始），尽管他最快也是在刺杀格里马尔迪 后拿到此剑的。